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SCIENCE
New science.
New hope.
Hair Follicle Cross Section
SCIENCE
New science.
New hope.

It's been decades since anyone's made meaningful advancements in the hair health industry. But a new world of science and research has just changed the way we think about hair and its relationship to our overall health.

It's been decades since anyone's made meaningful advancements in the hair health industry.

It's not just genetics that have it out for your hair. Stress, DHT levels, diet and environmental toxins all have been discovered to compromise hair health. Leveraging the latest, greatest in biotechnology,
A new world of science and research has just changed the way we think about hair and its relationship to our overall health. We discovered that it’s not just genetics that have it out for your hair. Stress, DHT levels, diet and environmental toxins all have been discovered to compromise hair health.
Nutrafol's 100% drug-free botanical ingredients are shown to target the multiple causes of thinning hair without compromising sexual health, or any other kind.
Leveraging the latest, greatest in biotechnology, Nutrafol’s 100% drug-free botanical ingredients are shown to target the multiple causes of thinning hair without compromising sexual health, or any other kind.
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Journal of Drugs in Dermatology Cover and Pages
The evidence is piling up faster than the hair in your drain.
Our secret weapon is science. Plus, researchers, dermatologists, clinical studies, over 1100 physicians, and peer-reviewed research like this from the Journal of Drugs in Dermatology, in which Nutrafol is proudly included.
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Common misconceptions about hair
thinning vs. new science findings:

1.
Stress
MISCONCEPTION:
Stress plays a role only in sudden hair shedding.
NEW SCIENCE FINDINGS:
Stress plays a leading role in ALL hair health issues. In fact, science shows that elevated levels of chronic stress generate chemical molecules that disrupt hair growth cycle signaling & need to be addressed.
1. Stress
MISCONCEPTION:
Stress plays a role only in sudden hair shedding.
NEW SCIENCE FINDINGS:
Stress plays a leading role in ALL hair health issues. In fact, science shows that elevated levels of chronic stress generate chemical molecules that disrupt hair growth cycle signaling & need to be addressed.
2.
Genes
MISCONCEPTION:
Genes and nutritional deficiencies are usually behind the most common forms of poor hair health in men and women.
NEW SCIENCE FINDINGS:
In addition to genetics and nutritional deficiencies, there are other triggers at the root of poor hair health. Stress, environmental toxins (styling, products, tobacco), UV light, aging and free radicals have all been shown to play important roles in many hair issues, putting the follicle out of balance. New science confirms that all these triggers lead to a cascade producing chemical molecules that disrupt optimal hair growth cycle signaling.
2. Genes
MISCONCEPTION:
Genes and nutritional deficiencies are usually behind the most common forms of poor hair health in men and women.
NEW SCIENCE FINDINGS:
In addition to genetics and nutritional deficiencies, there are other triggers at the root of poor hair health. Stress, environmental toxins (styling, products, tobacco), UV light, aging and free radicals have all been shown to play important roles in many hair issues, putting the follicle out of balance. New science confirms that all these triggers lead to a cascade producing chemical molecules that disrupt optimal hair growth cycle signaling.
3.
Mono-targeting
MISCONCEPTION:
Mono-targeting by addressing androgens like DHT is the standard of care.
NEW SCIENCE FINDINGS:
A long-term solution requires that MULTIPLE triggers at the root of poor hair health and their consequences (free radicals, damaging chemical molecules) be addressed in a multi-targeted, multi-step approach.
3. Mono-targeting
MISCONCEPTION:
Mono-targeting by addressing androgens like DHT is the standard of care.
NEW SCIENCE FINDINGS:
A long-term solution requires that MULTIPLE triggers at the root of poor hair health and their consequences (free radicals, damaging chemical molecules) be addressed in a multi-targeted, multi-step approach.
INTERNAL TRIGGERSshort line
EXTERNAL TRIGGERSshort line
Internal and External Triggers
Natural Aging
Process
Internal and External Triggers
DHT hormone
(genes)
Internal and External Triggers
Cortisol hormone
(stress)
Internal and External Triggers
Diet
nutrition
Internal and External Triggers
UV
Exposure
Internal and External Triggers
Product
Styling
Internal and External Triggers
Pollution
Internal and External Triggers
Extreme
Training
INTERNAL TRIGGERS
Internal and External Triggers
Natural Aging
Process
Internal and External Triggers
DHT hormone
(genes)
Internal and External Triggers
Cortisol hormone
(stress)
Internal and External Triggers
Diet
nutrition
short line
EXTERNAL TRIGGERS
Internal and External Triggers
UV
Exposure
Internal and External Triggers
Product
Styling
Internal and External Triggers
Pollution
Internal and External Triggers
Extreme
Training
an open bottle of Nutrafol seen from overhead

The effects of internal and external triggers

The hair follicle is a dynamic mini-organ that undergoes perfectly calibrated cycles of growth, regression and rest.

Each follicle has its own independent biological clock that ticks and signals the follicle to grow hair, lose hair or lay dormant. When out of balance, under attack, or its environment is altered, the process of hair production is disrupted.

New science proves how a multitude of internal and external triggers create an imbalance in the body’s immune system and metabolic pathways.

At the follicle, this produces a cascade of free radicals, oxidative stress and inflammatory markers.

These factors generate damaging molecules and more free radicals that lead to disruption of the hair cycle. This prompts the follicle and the immune system to respond by producing more of these chemical molecules, called cytokines, which start to affect our hair.

an open bottle of Nutrafol seen from overhead
Multiple triggers lead to:
1.
Dysregulated signaling molecules
1. Dysregulated signaling molecules
Inflammatory markers, free radicals and damaging chemical molecules disrupt the signaling molecules responsible for regulating the hair growth cycle and hair production. Signaling Molecules — when not properly regulated — will disrupt a healthy hair- growth cycle and follicle growth by sending a signal to the follicle to move into catagen (regression) phase, rather than anagen (growth) phase; and anagen signaling is essential for these hairs to be replaced. This is the beginning of hair thinning. Simply put: You are not replacing the 100-200 hairs that normally fall out per day at the same rate.
micro-inflammation overview
2.
Deficient nutrient absorption and delivery
2. Deficient nutrient absorption and delivery
In addition to the hair growth cycle being altered and the follicle being imbalanced, the ongoing cascade leads to another important consequence:
  • The efficient delivery of nutrients to the follicle is compromised
  • The ability of the follicle to absorb nutrients is dramatically diminished
Our researchers coined the term DNAD or deficient nutrient absorption and delivery to describe the impoverished state of the follicle, which is essentially being starved as a result.
nutrient absorption overview
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Comprehensive solution in a four-step protocol
Nutrafol, utilizes a full spectrum of standardized nutraceutical-grade phyto-nutrients, leveraging the multi-dimensional properties of therapeutic nutraceuticals that work in synergy to improve hair health. Scientifically formulated, Nutrafol takes a four-stage approach to jumpstart your healthy hair growth cycle from the inside out.
After years of research, the makers of Nutrafol deduced that if a long-term solution to thinning hair with sustainable efficacy were to exist, it would have to do the following:
multitarget icon
Synergistically target all potential triggering factors of hair thinning.
follicle icon
Remove the follicle from the state of DNAD, recalibrate its signaling, and optimize its environment—empowering it to heal.
cycle icon
Break the ongoing cascade that disrupts hair growth, cycling and signaling.
building blocks icon
Stimulate the growth cycle and provide the building blocks for healthy hair once balance is established.
open bottle of Nutrafol spilled
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Nutrafol science research and therapeutic nutraceuticals are redefining the science of hair health.
NEW THINKING
NUTRAFOL® FINDINGS
NUTRACEUTICAL BENEFITS
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1.
The concept of mono-targeting single triggers is outdated.
Targeting single triggers, like only DHT, or simply providing nutrition (vitamins and minerals) to hair follicles that are compromised is not enough to return to a healthier hair growth cycle.
Powerful therapeutic plants have been identified and now scientifically proven to target multiple triggers and offensive molecules that are triggers of an imbalanced follicle, such as DHT, stress hormones and free radicals.
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2.
The cascade of free radicals and disruptive signaling must be broken.
It is not enough to simply remove the initial triggers once the cascade has begun, as it will continue dysregulating normal hair growth, cycling and signaling.
Nutrafol® uses powerful nutraceutical–grade botanical ingredients that help address triggers like stress levels and free radicals that interrupt optimal hair growth.
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3.
Follicle healing must be empowered by boosting and optimizing the body’s innate healing and protective mechanisms.
Our bodies have all they need to heal and protect us. But with the challenges of daily life (stress, free radicals, aging), the innate mechanisms that support healing (the immune and antioxidant systems) become depleted. Each follicle has an additional ability to shield itself from these triggers, however, even this protective system has been shown to collapse from emotional and physical stress. So it is important to not only combat triggers and damaging molecules, but to also optimize the body’s natural mechanisms that promote healing and empower the follicle to remove itself from the state of DNAD.
The healing properties of potent therapeutic plants within Nutrafol® have also been proven to raise levels of the body’s natural (endogenous) antioxidant defenses, combat aging, increase factors that support the follicle, and boost the immune system – empowering the damaged follicles to heal from within. These same botanicals act to synergistically improve blood flow and the structural integrity of the scalp – supporting the follicle as it begins absorbing nutrients again.
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4.
Hair growth should be supported and stimulated.
In addition to providing vitamins, minerals and other nutritive building blocks, for healthy hair growth to occur, the hair growth cycle should be stimulated.
It has been shown that these powerfully efficacious phyto-nutrients also have synergistic abilities to increase production of signaling molecules that normally stimulate the follicles to enter into anagen (growth phase of the hair cycle).